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Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs

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Niedermair, Tanja ; Lukas, Christoph ; Li, Shushan ; Stöckl, Sabine ; Craiovan, Benjamin ; Brochhausen, Christoph ; Federlin, Marianne ; Herrmann, Marietta ; Grässel, Susanne
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 26 Feb 2021 18:25


Background: Studies with extracellular vesicles (EVs), including exosomes, isolated from mesenchymal stem cells (MSC) indicate benefits for the treatment of musculoskeletal pathologies as osteoarthritis (OA) and osteoporosis (OP). However, little is known about intercellular effects of EVs derived from pathologically altered cells that might influence the outcome by counteracting effects from ...


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