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Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are not associated with severity of liver disease and are inversely related to cholesterol in a cohort of thirty eight patients with liver cirrhosis

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Feder, Susanne ; Wiest, Reiner ; Weiss, Thomas S. ; Aslanidis, Charalampos ; Schacherer, Doris ; Krautbauer, Sabrina ; Liebisch, Gerhard ; Buechler, Christa
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 23 Feb 2021 13:16


Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is of particular importance in cholesterol metabolism with high levels contributing to hypercholesterolemia. Cholesterol and sphingolipids are low in patients with liver cirrhosis. Purpose of this study was to find associations of plasma PCSK9 with circulating cholesterol and sphingolipid species and measures of liver disease ...


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