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Effects of sodium chloride on the gene expression profile of periodontal ligament fibroblasts during tensile strain

Schröder, Agnes ; Gubernator, Joshua ; Nazet, Ute ; Spanier, Gerrit ; Jantsch, Jonathan ; Proff, Peter ; Kirschneck, Christian


Purpose During orthodontic tooth movement, pressure and tension zones develop in the periodontal ligament, and periodontal ligament fibroblasts (PDLF) become exposed to mechanical strain. Enhanced salt (NaCl) concentrations are known to modulate responses of PDLF and immune cells to different stimuli like mechanical strain. Here, we investigated the impact of tensile strain on the gene expression ...


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