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Application of Lipid Class Ratios for Sample Stability Monitoring—Evaluation of Murine Tissue Homogenates and SDS as a Stabilizer

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Sigrüner, Alexander ; Krautbauer, Sabrina ; Blazquez, Raquel ; Liebisch, Gerhard ; Hoering, Marcus ; Neubert, Philip ; Pukrop, Tobias ; Burkhardt, Ralph
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 25 Jun 2021 15:52


Lipids are a ubiquitous class of structurally complex molecules involved in various biological processes. In the fast-growing field of lipidomics, preanalytical issues are frequently neglected. Here, we investigated the stability of lipid profiles of murine liver, brain, lung, heart, and spleen homogenates by quantitative flow injection analysis using tandem mass spectrometry and high-resolution ...


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