In this paper, we summarize our efforts in simulating Yang-Mills theories coupled to matter fields transforming under the fundamental and adjoint representations of the gauge group. In the context of composite Higgs scenarios, gauge theories with mixed representation fields have been suggested to describe the fundamental interactions well beyond the electroweak unification scale, and they are also closely related to supersymmetric QCD. In addition, they are studied as deformations of theories with pure adjoint matter in the context of adiabatic continuity. We provide some first results for bare parameter tuning and interdependence of the two representations. We also investigate how the chiral symmetry breaking or a conformal scenario can be realized and checked in such theories.