Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans

URN to cite this document:: urn:nbn:de:bvb:355-epub-459394
DOI to cite this document:: 10.5283/epub.45939

Kirschneck, Christian

; Silva-Sousa, Alice Correa ; Maranon-Vasquez, Guido Artemio ; Stuani, Maria Bernadete Sasso ; Proff, Peter ; Andrades, Kesly Mary Ribeiro ; Baratto-Filho, Flares ; Matsumoto, Mirian Aiko Nakane ; Paddenberg, Eva ; Küchler, Erika Calvano

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Date of publication of this fulltext: 10 Feb 2022 16:17

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Abstract

This study investigated, if genetic variants in BMP2, BMP4 and SMAD6 are associated with variations in the palatal rugae pattern in humans. Dental casts and genomic DNA from 75 patients were evaluated. Each patient was classified as follows: total amount of rugae; bilateral symmetry in the amount, length and shape of the palatal rugae; presence of secondary or fragmentary palatal rugae; presence ...