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Virus-Mimetic Nanoparticles for the Therapy of Mesangial Cells in Diabetic Nephropathy
Fleischmann, Daniel (2021) Virus-Mimetic Nanoparticles for the Therapy of Mesangial Cells in Diabetic Nephropathy. PhD, Universität Regensburg.Date of publication of this fulltext: 30 Jun 2021 07:56
Thesis of the University of Regensburg
DOI to cite this document: 10.5283/epub.46170
Abstract (English)
In this work, adenovirus-mimetic nanoparticles with a sequential target cell recognition were manufactured to treat renal mesangial cells in diabetic nephropathy via cell-specific delivery of anti-fibrotic agent cinaciguat.
Translation of the abstract (German)
In dieser Arbeit wurden Adenovirus-mimetische Nanopartikel mit einem sequenziellen Erkennungsprinzip für renale Mesangialzellen hergestellt. Ziel war es dabei, den antifibrotischen Wirkstoff Cinaciguat zielgerichtet zu Mesangialzellen zu transportieren, um diese im Rahmen der Diabetischen Nephropathie zu therapieren.
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Details
| Item type | Thesis of the University of Regensburg (PhD) |
| Open Access Type: | Primary Publication |
|---|---|
| Date | 30 June 2021 |
| Referee | Prof. Dr. Achim Göpferich |
| Date of exam | 18 June 2021 |
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich) |
| Keywords | Virus-mimetic Nanoparticles, Anti-Fibrotic Therapy, Renal Mesangial Cells |
| Dewey Decimal Classification | 500 Science > 500 Natural sciences & mathematics 500 Science > 540 Chemistry & allied sciences |
| Status | Published |
| Refereed | Yes, this version has been refereed |
| Created at the University of Regensburg | Yes |
| URN of the UB Regensburg | urn:nbn:de:bvb:355-epub-461702 |
| Item ID | 46170 |
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