A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

URN to cite this document:: urn:nbn:de:bvb:355-epub-461782
DOI to cite this document:: 10.5283/epub.46178

Poppelaars, Felix ; Goicoechea de Jorge, Elena ; Jongerius, Ilse ; Baeumner, Antje J. ; Steiner, Mark-Steven ; Józsi, Mihály ; Toonen, Erik J. M. ; Pauly, Diana

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Date of publication of this fulltext: 26 Jun 2021 09:39

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Abstract

Inflammation is a common denominator of diseases. The complement system, an intrinsic part of the innate immune system, is a key driver of inflammation in numerous disorders. Recently, a family of proteins has been suggested to be of vital importance in conditions characterized by complement dysregulation: the human Factor H (FH) family. This group of proteins consists of FH, Factor H-like ...