Go to content
UR Home

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney

Rampanelli, Elena ; Ochodnicky, Peter ; Vissers, Johannes P. C. ; Butter, Loes M. ; Claessen, Nike ; Calcagni, Alessia ; Kors, Lotte ; Gethings, Lee A. ; Bakker, Stephan J. L. ; de Borst, Martin H. ; Navis, Gerjan J. ; Liebisch, Gerhard ; Speijer, Dave ; van den Bergh Weerman, Marius A. ; Jung, Bettina ; Aten, Jan ; Steenbergen, Eric ; Schmitz, Gerd ; Ballabio, Andrea ; Florquin, Sandrine ; Aerts, Johannes M. F. G. ; Leemans, Jaklien C.


Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney disease. The cellular mechanisms connecting metabolic syndrome with chronic kidney disease onset and progression remain largely unclear. We show that proximal tubular epithelium is a target site for lipid deposition upon overnutrition with a cholesterol-rich Western-type diet. Affected proximal ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons