Go to content
UR Home

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

De Schepper, Sebastiaan ; Verheijden, Simon ; Aguilera-Lizarraga, Javier ; Viola, Maria Francesca ; Boesmans, Werend ; Stakenborg, Nathalie ; Voytyuk, Iryna ; Schmidt, Inga ; Boeckx, Bram ; Dierckx de Casterlé, Isabelle ; Baekelandt, Veerle ; Gonzalez Dominguez, Erika ; Mack, Matthias ; Depoortere, Inge ; De Strooper, Bart ; Sprangers, Ben ; Himmelreich, Uwe ; Soenen, Stefaan ; Guilliams, Martin ; Vanden Berghe, Pieter ; Jones, Elizabeth ; Lambrechts, Diether ; Boeckxstaens, Guy



Abstract

Macrophages are highly heterogeneous tissue-resident immune cells that perform a variety of tissue- supportive functions. The current paradigm dictates that intestinal macrophages are continuously replaced by incoming monocytes that acquire a pro-inflammatory or tissue-protective signature. Here, we identify a self-maintaining population of macrophages that arise from both embryonic precursors ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons