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MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines

Burla, Bo ; Arita, Makoto ; Arita, Masanori ; Bendt, Anne K. ; Cazenave-Gassiot, Amaury ; Dennis, Edward A. ; Ekroos, Kim ; Han, Xianlin ; Ikeda, Kazutaka ; Liebisch, Gerhard ; Lin, Michelle K. ; Loh, Tze Ping ; Meikle, Peter J. ; Orešič, Matej ; Quehenberger, Oswald ; Shevchenko, Andrej ; Torta, Federico ; Wakelam, Michael J. O. ; Wheelock, Craig E. ; Wenk, Markus R.


Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) offers insights into individual metabolism and physiology in health and disease. Disturbances in the plasma lipidome also occur in conditions that are not directly linked to lipid metabolism; therefore, plasma ...


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