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Circulating and Tumor Myeloid-derived Suppressor Cells in Resectable Non–Small Cell Lung Cancer

Yamauchi, Yoshikane ; Safi, Seyer ; Blattner, Carolin ; Rathinasamy, Anchana ; Umansky, Ludmila ; Juenger, Simone ; Warth, Arne ; Eichhorn, Martin ; Muley, Thomas ; Herth, Felix J. F. ; Dienemann, Hendrik ; Platten, Michael ; Beckhove, Philipp ; Utikal, Jochen ; Hoffmann, Hans ; Umansky, Viktor



Abstract

Rationale: Myeloid-derived suppressor cell (MDSC) expansion has been found to play a role in disease progression in patients with cancer. However, the characteristics of MDSCs in lung cancer are poorly understood. Objectives: We prospectively investigated MDSCs and inflammatory factors in tumor and peripheral blood samples from patients with resectable non-small cell lung cancer and studied their ...

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