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Expression kinetics of human periodontal ligament fibroblasts in the early phases of orthodontic tooth movement

Schröder, Agnes ; Bauer, Kathrin ; Spanier, Gerrit ; Proff, Peter ; Wolf, Michael ; Kirschneck, Christian



Abstract

Purpose Human periodontal ligament (hPDL) fibroblasts play a crucial mediating role in orthodontic tooth movement (OTM). In this study, we investigated the expression kinetics of genes associated with OTM in its early phase to obtain better insight into the timing and regulation of molecular and cellular signalling and transformation processes occurring in compressive areas of the periodontal ...

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