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A Validated, Fast Method for Quantification of Sterols and Gut Microbiome Derived 5α/β-Stanols in Human Feces by Isotope Dilution LC–High-Resolution MS

Schött, Hans-Frieder ; Krautbauer, Sabrina ; Höring, Marcus ; Liebisch, Gerhard ; Matysik, Silke


There has been an increasing interest during recent years in the role of the gut microbiome on health and disease. Therefore, metabolites in human feces related to microbial activity are attractive surrogate marker to track changes of microbiota induced by diet or disease. Such markers include 5 alpha/beta-stanols as microbiome-derived metabolites of sterols. Currently, reliable, robust, and fast ...


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