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Cold atmospheric plasma causes a calcium influx in melanoma cells triggering CAP-induced senescence

Schneider, Christin ; Gebhardt, Lisa ; Arndt, Stephanie ; Karrer, Sigrid ; Zimmermann, Julia L. ; Fischer, Michael J. M. ; Bosserhoff, Anja-Katrin



Abstract

Cold atmospheric plasma (CAP) is a promising approach in anti-cancer therapy, eliminating cancer cells with high selectivity. However, the molecular mechanisms of CAP action are poorly understood. In this study, we investigated CAP effects on calcium homeostasis in melanoma cells. We observed increased cytoplasmic calcium after CAP treatment, which also occurred in the absence of extracellular ...

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