Go to content
UR Home

Transition-State Ensembles Navigate the Pathways of Enzyme Catalysis

Mickert, Matthias J. ; Gorris, Hans H.


Transition-state theory (TST) provides an important framework for analyzing and explaining the reaction rates of enzymes. TST, however, needs to account for protein dynamic effects and heterogeneities in enzyme catalysis. We have analyzed the reaction rates of beta-galactosidase and beta-glucuronidase at the single molecule level by using large arrays of femtoliter-sized chambers. Heterogeneities ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons