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Cell Homing for Pulp Tissue Engineering with Endogenous Dentin Matrix Proteins

Widbiller, Matthias ; Driesen, Ronald B. ; Eidt, Andreas ; Lambrichts, Ivo ; Hiller, Karl-Anton ; Buchalla, Wolfgang ; Schmalz, Gottfried ; Galler, Kerstin M.


Introduction: Compelling evidence pinpoints that pulp tissue engineering after the transplantation of stem cells is possible. Although intriguing, severe problems regarding clinical feasibility remain. Cell homing has been proposed as a viable alternative in which dentin derived growth factors in a conducive scaffold may attract resident cells to form pulplike tissue. In this study, an ectopic ...


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