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Infiltrative lamina propria invasion pattern as an independent predictor for cancer-specific and overall survival of instillation treatment-naïve stage T1 high-grade urothelial bladder cancer

Otto, Wolfgang ; van Rhijn, Bas W. G. ; Breyer, Johannes ; Bertz, Simone ; Eckstein, Markus ; Mayr, Roman ; Lausenmeyer, Eva M. ; Denzinger, Stefan ; Burger, Maximilian ; Hartmann, Arndt


ObjectivesTo investigate established prognostic factors and relatively new histopathological tumor characteristics including metric substage and lamina propria invasion patterns in a large series of T1 high-grade non-muscle-invasive bladder cancer. MethodsBetween 1989 and 2012, 322 patients with initial stageT1 high-grade bladder cancer underwent transurethral resection, followed by ...


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