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A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients

Batschkus, Sarah ; Cingoez, Goekhan ; Urlaub, Henning ; Miosge, Nicolai ; Kirschneck, Christian ; Meyer-Marcotty, Philipp ; Lenz, Christof



Abstract

Gingival crevicular fluid (GCF), the inflammatory infiltrate within the crevicular sulcus, is of great importance for diverse processes in the oral cavity and has a high impact in oral sciences. It is assumed to serve as a source of biomarkers for systemic or periodontal diseases and mediators of orthodontic tooth movement. In order to characterize the protein content of the GCF in an unbiased ...

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