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p53-expression in patients with renal cell carcinoma correlates with a higher probability of disease progression and increased cancer-specific mortality after surgery but does not enhance the predictive accuracy of robust outcome models

Morshaeuser, Laura ; May, Matthias ; Burger, Maximilian ; Otto, Wolfgang ; Hutterer, Georg C. ; Pichler, Martin ; Klatte, Tobias ; Wild, Peter ; Buser, Lorenz ; Brookman-May, Sabine



Zusammenfassung

Objective: Due to lacking external validation, molecular biomarkers are currently not applied for risk-stratification of patients with localized renal cell carcinoma. The objective of this study was to externally validate a molecular multi-marker panel included in a previously proposed prognostic nomogram for the prediction of postoperative disease-free survival. Methods and materials: Besides ...

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