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Predicting Early Viral Control under Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus Using Pretreatment Immunological Markers

Hutchinson, James A. ; Weigand, Kilian ; Adenugba, Akinbami ; Kronenberg, Katharina ; Haarer, Jan ; Zeman, Florian ; Riquelme, Paloma ; Hornung, Matthias ; Ahrens, Norbert ; Schlitt, Hans J. ; Geissler, Edward K. ; Werner, Jens M.


Recent introduction of all-oral direct-acting antiviral (DAA) treatment has revolutionized care of patients with chronic hepatitis C virus (HCV) infection. Regrettably, the high cost of DAA treatment is burdensome for healthcare systems and may be prohibitive for some patients who would otherwise benefit. Understanding how patient-related factors influence individual responses to DAA treatment ...


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