Go to content
UR Home

Indoxyl 3-sulfate inhibits maturation and activation of human monocyte-derived dendritic cells

Ghimire, Sakhila ; Matos, Carina ; Caioni, Massimiliano ; Weber, Daniela ; Peter, Katrin ; Holler, Ernst ; Kreutz, Marina ; Renner, Kathrin



Abstract

Indole is produced from L-tryptophan by commensal bacteria and further metabolized to indoxyl 3-sulfate (I3S) in the liver. Physiologic concentrations of I3S are related to a lower risk to develop graft versus host disease in allogeneic stem cell transplanted patients pointing towards an immunoregulatory function of I3S. Here we investigated the impact of I3S on the maturation of human ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons