Go to content
UR Home

Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex

Naik, Roshan R. ; Sotnikov, Sergey V. ; Diepold, Rebekka P. ; Iurato, Stella ; Markt, Patrick O. ; Bultmann, Andrea ; Brehm, Nadine ; Mattheus, Tobias ; Lutz, Beat ; Erhardt, Angelika ; Binder, Elisabeth B. ; Schmidt, Ulrike ; Holsboer, Florian ; Landgraf, Rainer ; Czibere, Ludwig



Abstract

TMEM132D is a candidate gene, where risk genotypes have been associated with anxiety severity along with higher mRNA expression in the frontal cortex of panic disorder patients. Concurrently, in a high (HAB) and low (LAB) trait anxiety mouse model, Tmem132d was found to show increased expression in the anterior cingulate cortex (aCC) of HAB as compared to LAB mice. To understand the molecular ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: daten@ur.de
0941 943 -4239

Contact persons