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First experience of chick chorioallantoic membrane (CAM) assay in the clinical work flow with oral squamous cell carcinoma patients

Kauffmann, Philipp ; Troeltzsch, Markus ; Brockmeyer, Phillipp ; Bohnenberger, Hanibal ; Heidekrüger, Paul I. ; Manzke, Marietta ; Canis, Martin ; Gaayathiri, Suntharalingam ; Schliephake, Henning ; Prantl, Lukas ; Aung, Thiha ; Park, J.-W. ; Krüger, A. ; Jung, F.



Abstract

INTRODUCTION: The oral squamous cell carcinoma (OSCC) is a leading cause of death in human malignancies. The aim of this study is to integrate the CAM Assay as a reliable and good working in vivo model for the evaluation of OSCC tumor samples and its growth into the clinical work flow. MATERIAL AND METHODS: Fresh human Tumor samples (OSCCs) 1 x 1 cm in size were cut into 350-450 mu m thick slices ...

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