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Pigment-Dispersing Factor-expressing neurons convey circadian information in the honey bee brain

Beer, Katharina ; Kolbe, Esther ; Kahana, Noa B. ; Yayon, Nadav ; Weiss, Ron ; Menegazzi, Pamela ; Bloch, Guy ; Helfrich-Förster, Charlotte



Abstract

Pigment-Dispersing Factor (PDF) is an important neuropeptide in the brain circadian network of Drosophila and other insects, but its role in bees in which the circadian clock influences complex behaviour is not well understood. We combined high-resolution neuroanatomical characterizations, quantification of PDF levels over the day and brain injections of synthetic PDF peptide to study the role of ...

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