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Biological predictors of radiosensitivity in head and neck squamous cell carcinoma

Fiedler, Mathias ; Weber, Florian ; Hautmann, Matthias G. ; Haubner, Frank ; Reichert, Torsten E. ; Klingelhöffer, Christoph ; Schreml, Stephan ; Meier, Johannes K. ; Hartmann, Arndt ; Ettl, Tobias



Abstract

The aim of this study is to investigate the influence of prognostic biomarkers on radiosensitivity and survival of advanced head and neck squamous cell carcinomas treated by primary (chemo)radiation. The clinicopathological data and immunohistochemical staining of p16, c-Met, survivin, PD-1, and PD-L1 of 82 primarily (chemo)irradiated patients with head and neck squamous cell carcinoma were ...

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