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DAPK1 loss triggers tumor invasion in colorectal tumor cells

Steinmann, Sara ; Kunze, Philipp ; Hampel, Chuanpit ; Eckstein, Markus ; Bertram Bramsen, Jesper ; Muenzner, Julienne K. ; Carlé, Birgitta ; Ndreshkjana, Benardina ; Kemenes, Stephan ; Gasparini, Pierluigi ; Friedrich, Oliver ; Andersen, Claus ; Geppert, Carol ; Wang, Shengbao ; Eyupoglu, Ilker ; Bäuerle, Tobias ; Hartmann, Arndt ; Schneider-Stock, Regine


Colorectal cancer (CRC) is one of the leading cancer-related causes of death worldwide. Despite the improvement of surgical and chemotherapeutic treatments, as of yet, the disease has not been overcome due to metastasis to distant organs. Hence, it is of great relevance to understand the mechanisms responsible for metastasis initiation and progression and to identify novel metastatic markers for ...


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