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The MATH-BTB Protein TaMAB2 Accumulates in Ubiquitin-Containing Foci and Interacts With the Translation Initiation Machinery in Arabidopsis

Bauer, Nataša ; Škiljaica, Andreja ; Malenica, Nenad ; Razdorov, Genadij ; Klasić, Marija ; Juranić, Martina ; Močibob, Marko ; Sprunck, Stefanie ; Dresselhaus, Thomas ; Leljak Levanić, Dunja



Abstract

MATH-BTB proteins are known to act as substrate-specific adaptors of CUL3-based E3 ligases in the ubiquitin proteasome pathway. Their BTB domain binds to CUL3 scaffold proteins and the less conserved MATH domain targets a highly diverse collection of substrate proteins to promote their ubiquitination and subsequent degradation. In plants, a significant expansion of the MATH-BTB family occurred in ...

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