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Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial

Lanz, Jonas ; Kim, Won-Keun ; Walther, Thomas ; Burgdorf, Christof ; Möllmann, Helge ; Linke, Axel ; Redwood, Simon ; Thilo, Christian ; Hilker, Michael ; Joner, Michael ; Thiele, Holger ; Conzelmann, Lars ; Conradi, Lenard ; Kerber, Sebastian ; Schymik, Gerhard ; Prendergast, Bernard ; Husser, Oliver ; Stortecky, Stefan ; Heg, Dik ; Jüni, Peter ; Windecker, Stephan ; Pilgrim, Thomas


Background Transcatheter aortic valve replacement (TAVR) is the preferred treatment option for older patients with symptomatic severe aortic stenosis. Differences in the properties of available TAVR systems can affect clinical outcomes. Among patients undergoing TAVR, we compared the self-expanding ACURATE neo TAVR system with the balloon-expandable SAPIEN 3 TAVR system with regard to early ...


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