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Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation

Tiwari, Manu D. ; Zeitler, Daniela M. ; Meister, Gunter ; Wodarz, Andreas



Zusammenfassung

Stem cells can self-renew and produce daughter cells destined for differentiation. The precise control of the balance between these two outcomes is essential to ensure tissue homeostasis and to prevent uncontrolled proliferation resulting in tumor formation. As self-renewal and differentiation are likely to be controlled by different gene expression programs, unraveling the underlying gene ...

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