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Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma

Foertsch, Sandra ; Lackner, Ina ; Weber, Birte ; Füchsl, Andrea M. ; Langgartner, Dominik ; Wirkert, Eva ; Peters, Sebastian ; Fois, Giorgio ; Pressmar, Jochen ; Fegert, Jörg M. ; Frick, Manfred ; Gündel, Harald ; Kalbitz, Miriam ; Reber, Stefan O.


Cardiovascular disorders (CVD) and posttraumatic stress disorder (PTSD) are highly comorbid, but the underlying mechanisms are not fully understood. Chronic psychosocial stress was induced in male mice by chronic subordinate colony housing (CSC), a pre-clinically validated mouse model for PTSD. Cardiac structure and function were assessed on day 20 of the CSC paradigm. Following CSC, mice were ...


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