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Tissue expansion of lung bronchi due to tissue processing for histology – A comparative analysis of paraffin versus frozen sections in a pig model

Schmitt, Volker H. ; Schmitt, Christine ; Hollemann, David ; Weinheimer, Oliver ; Mamilos, Andreas ; Kirkpatrick, C. James ; Brochhausen, Christoph


Aim Tissue shrinking due to fixation and processing is well known. However, the degree of shrinking varies significantly with the tissue type as well as the processing method and is not well studied in various tissues. In daily pathological routine workflow, histological specimens from frozen and paraffin sections are performed from the same tissue. In the present study we compared the thickness ...


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