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Neurotrophic Proteins in Dentin and Their Effect on Trigeminal Sensory Neurons

Widbiller, Matthias ; Austah, Obadah ; Lindner, Sophia R. ; Sun, Jenny ; Diogenes, Anibal



Abstract

Introduction: A plethora of bioactive molecules present during tooth formation become sequestered in the mineralized dentin matrix and can be released into the pulp tissue after demineralization from carious lesions. However, neurotrophic factors are differentially expressed and secreted during various stages of odontogenesis. Thus, the aims of this study were (1) to investigate their presence ...

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