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Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease

Bartling, Babett ; Hofmann, Hans-Stefan


Background and objectivesThe prevalence of chronic obstructive pulmonary disease (COPD) and lung emphysema increases with age and both lung diseases are again risk factors for lung cancer. Since areduced capacity of fibroblasts for proliferation is agood indicator of tissue aging, we studied the cell proliferation of lung fibroblasts from normal and tumor tissue of lung cancer patients depending ...


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