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Androgen Receptor mRNA Expression in Urothelial Carcinoma of the Bladder: A Retrospective Analysis of Two Independent Cohorts

Sikic, Danijel ; Wirtz, Ralph M. ; Wach, Sven ; Dyrskjøt, Lars ; Erben, Philipp ; Bolenz, Christian ; Breyer, Johannes ; Otto, Wolfgang ; Hoadley, Katherine A. ; Lerner, Seth P. ; Eckstein, Markus ; Hartmann, Arndt ; Keck, Bastian



Abstract

INTRODUCTION: Gender-specific differences have led to the androgen receptor (AR) being considered a possible factor in the pathophysiology of urothelial carcinoma of the bladder (UCB), but the exact role remains unclear. MATERIALS AND METHODS: The association of AR mRNA expression with clinicopathological features was retrospectively analyzed in two previously described cohorts. The first cohort ...

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