Miner, Kent ; Labitzke, Katja ; Liu, Benxian ; Wang, Paul ; Henckels, Kathryn ; Gaida, Kevin ; Elliott, Robin ; Chen, Jian Jeffrey ; Liu, Longbin ; Leith, Anh ; Trueblood, Esther ; Hensley, Kelly ; Xia, Xing-Zhong ; Homann, Oliver ; Bennett, Brian ; Fiorino, Mike ; Whoriskey, John ; Yu, Gang ; Escobar, Sabine ; Wong, Min ; Born, Teresa L. ; Budelsky, Alison ; Comeau, Mike ; Smith, Dirk ; Phillips, Jonathan 
; Johnston, James A. ; McGivern, Joseph G. ; Weikl, Kerstin ; Powers, David ; Kunzelmann, Karl ; Mohn, Deanna ; Hochheimer, Andreas ; Sullivan, John K.
; Johnston, James A. ; McGivern, Joseph G. ; Weikl, Kerstin ; Powers, David ; Kunzelmann, Karl ; Mohn, Deanna ; Hochheimer, Andreas ; Sullivan, John K. Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways
Article
Miner, Kent, Labitzke, Katja, Liu, Benxian, Wang, Paul, Henckels, Kathryn, Gaida, Kevin, Elliott, Robin, Chen, Jian Jeffrey, Liu, Longbin, Leith, Anh, Trueblood, Esther, Hensley, Kelly, Xia, Xing-Zhong, Homann, Oliver, Bennett, Brian, Fiorino, Mike, Whoriskey, John, Yu, Gang, Escobar, Sabine, Wong, Min, Born, Teresa L., Budelsky, Alison, Comeau, Mike, Smith, Dirk, Phillips, Jonathan, Johnston, James A., McGivern, Joseph G., Weikl, Kerstin, Powers, David, Kunzelmann, Karl, Mohn, Deanna, Hochheimer, Andreas and Sullivan, John K.
(2019)
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Frontiers in Pharmacology 10.
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Details
| Item type | Article | ||||
| Journal or Publication Title | Frontiers in Pharmacology | ||||
| Publisher | Frontiers | ||||
| Place of Publication | LAUSANNE | ||||
| Volume | 10 | ||||
| Date | 2019 | ||||
| Date of publication | 03 Sep 2021 10:04 | ||||
| Institutions | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann | ||||
| Identification Number |
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| Keywords | ACTIVATED CHLORIDE CHANNEL; CA2+-ACTIVATED CL-CHANNEL; SMOOTH-MUSCLE-CELLS; ANOCTAMIN 1; ASTHMA PHENOTYPES; MUCIN SECRETION; ANIMAL-MODELS; EXPRESSION; CANCER; CURRENTS; TMEM16A antagonist; niclosamide; nitazoxanide; bronchodilator; desensitization; airway smooth muscle (ASM); calcium-activated chloride channel; drug repositioning | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 48982 |
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