Go to content
UR Home

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

Zubiete-Franco, Imanol ; García-Rodríguez, Juan L. ; Lopitz-Otsoa, Fernando ; Serrano-Macia, Marina ; Simon, Jorge ; Fernández-Tussy, Pablo ; Barbier-Torres, Lucía ; Fernández-Ramos, David ; Gutiérrez-de-Juan, Virginia ; López de Davalillo, Sergio ; Carlevaris, Onintza ; Beguiristain Gómez, Adolfo ; Villa, Erica ; Calvisi, Diego ; Martín, César ; Berra, Edurne ; Aspichueta, Patricia ; Beraza, Naiara ; Varela-Rey, Marta ; Ávila, Matias ; Rodríguez, Manuel S. ; Mato, José M. ; Díaz-Moreno, Irene ; Díaz-Quintana, Antonio ; Delgado, Teresa C. ; Martínez-Chantar, María L.



Abstract

Background: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular Carcinoma (HCC). Methods: Herein we have overexpressed LKB1 in human hepatoma cells and by using histidine pull-down assay we have investigated the role of the hypoxia-related ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons