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Hoffmann, Anna-Carin ; Minakaki, Georgia ; Menges, Stefanie ; Salvi, Rachele ; Savitskiy, Sergey ; Kazman, Aida ; Vicente Miranda, Hugo ; Mielenz, Dirk ; Klucken, Jochen ; Winkler, Jürgen ; Xiang, Wei

Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose

Hoffmann, Anna-Carin, Minakaki, Georgia , Menges, Stefanie, Salvi, Rachele, Savitskiy, Sergey, Kazman, Aida, Vicente Miranda, Hugo , Mielenz, Dirk, Klucken, Jochen, Winkler, Jürgen and Xiang, Wei (2019) Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Scientific Reports 9 (1).

Date of publication of this fulltext: 03 Sep 2021 10:05
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Item typeArticle
Journal or Publication TitleScientific Reports
Publisher:Nature
Place of Publication:LONDON
Volume:9
Number of Issue or Book Chapter:1
Date2019
InstitutionsMedicine > Lehrstuhl für Humangenetik
Identification Number
ValueType
10.1038/s41598-018-35811-8DOI
KeywordsCOMPLEX-I; DOPAMINERGIC-NEURONS; PARKINSONS-DISEASE; LEWY BODIES; AUTOPHAGY; ACCUMULATION; OLIGOMERS; MITOPHAGY; ENDOCYTOSIS; CLEARANCE;
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID49076

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