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Establishment of a clinically relevant large animal model to assess the healing of metaphyseal bone

Alagboso, FI. ; Budak, M. ; Sommer, U. ; Ray, S. ; Kaiser, A. ; Kampschulte, M. ; Henss, A. ; Dürselen, L. ; Biehl, C. ; Lips, K. S. ; Heiss, C. ; Thormann, U. ; Alt, V.


Despite the high incidence of metaphyseal bone fractures in patients, the mechanisms underlying the healing processes are poorly understood due to the lack of suitable experimental animal models. Hence, the present study was conducted to establish and characterise a clinically relevant large-animal model for metaphyseal bone healing. Six female adult Merino sheep underwent full wedge-shaped ...


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