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Long-Chain Fatty Acids and Inflammatory Markers Coaccumulate in the Skeletal Muscle of Sarcopenic Old Rats

Laurentius, Thea ; Kob, Robert ; Fellner, Claudia ; Nourbakhsh, Mahtab ; Bertsch, Thomas ; Sieber, Cornel Christian ; Bollheimer, Leo Cornelius


Obesity and inflammation are reportedly associated with the pathogenesis of sarcopenia, which is characterized by age-related loss of skeletal muscle mass. Intramuscular fat deposits have been found to compromise muscle integrity; however, the relevant fat compounds and their roles as mediators of muscular inflammation are not known. The aim of this study was to identify potential correlations ...


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