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Characterization of septin expression in normal and fibrotic kidneys

Neubauer, Katharina ; Neubauer, Bjoern ; Seidl, Maximilian ; Zieger, Barbara



Abstract

Chronic kidney disease (CKD) is characterized by the loss of nephrons and worsening organ-fibrosis that leads to deterioration and ultimately the total breakdown of kidney function. Renal fibrosis has become a major public health problem worldwide and necessitates hemodialysis and kidney transplantation in affected patients. CKD is mainly characterized by the activation and proliferation of ...

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