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High proliferation rate and TNM stage but not histomorphological subtype are independent prognostic markers for overall survival in papillary renal cell carcinoma

Polifka, Iris ; Agaimy, Abbas ; Herrmann, Edwin ; Spath, Verena ; Trojan, Lutz ; Stöckle, Michael ; Becker, Frank ; Ströbel, Philipp ; Wülfing, Christian ; Schrader, Andres J. ; Barth, Peter ; Staehler, Michael ; Stief, Christian ; Hohenfellner, Markus ; Macher-Göppinger, Stephan ; Wullich, Bernd ; Noldus, Joachim ; Brenner, Walburgis ; Roos, Frederik C. ; Walter, Bernhard ; Otto, Wolfgang ; Burger, Maximilian ; Höfler, Heinz ; Haferkamp, Axel ; Geppert, Carol I. ; Stöhr, Christine ; Hartmann, Arndt



Abstract

Papillary renal cell carcinoma (PRCC) is currently divided in 2 subtypes. We reviewed a large cohort of PRCC and correlated subtype, morphological features and diagnostic marker expression with overall survival (OS) to uncover differences between the 2 subtypes. Three hundred seventy-six renal tumors initially diagnosed as PRCC with clinical and survival data were collected from the participating ...

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