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Photosensitiser functionalised luminescent upconverting nanoparticles for efficient photodynamic therapy of breast cancer cells

Buchner, Markus ; García Calavia, Paula ; Muhr, Verena ; Kröninger, Anna ; Baeumner, Antje J. ; Hirsch, Thomas ; Russell, David A. ; Marín, María J.


Photodynamic therapy (PDT) is a well-established treatment of cancer in which cell toxic reactive oxygen species, including singlet oxygen (O-1(2)), are produced by a photosensitiser drug following irradiation of a specific wavelength. Visible light is commonly used as the excitation source in PDT, although these wavelengths do have limited tissue penetration. In this research, upconverting ...


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