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Microcosm biofilms cultured from different oral niches in periodontitis patients

Cieplik, Fabian ; Zaura, Egija ; Brandt, Bernd W. ; Buijs, Mark J. ; Buchalla, Wolfgang ; Crielaard, Wim ; Laine, Marja L. ; Deng, Dong Mei ; Exterkate, Rob A. M.


Objective: Periodontal diseases are triggered by dysbiotic microbial biofilms. Therefore, it is essential to develop appropriate biofilm models. Aim of the present study was to culture microcosm biofilms inoculated from different niches in periodontitis patients and compare their microbial composition to those inoculated from subgingival plaque. Methods: Saliva, subgingival plaque, tongue and ...


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