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Neutrophils—From Bone Marrow to First-Line Defense of the Innate Immune System

URN to cite this document:
urn:nbn:de:bvb:355-epub-492494
DOI to cite this document:
10.5283/epub.49249
Kraus, Richard F. ; Gruber, Michael A.
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 31 Jan 2022 13:20



Abstract

Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens and are therefore an important component of the innate immune response. As a result of poorly controlled activation, however, PMNs can also mediate tissue damage in numerous diseases, often by increasing tissue inflammation and injury. According to current knowledge, PMNs are not only part of the ...

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