Total platelet donation count and donation frequency are determinants of plateletpheresis‐associated lymphopenia

URN to cite this document:: urn:nbn:de:bvb:355-epub-493382
DOI to cite this document:: 10.5283/epub.49338

Thuer, Linda ; Brosig, Andreas ; Hutchinson, James A. ; Hähnel, Viola ; Offner, Robert ; Burkhardt, Ralph

; Ahrens, Norbert

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Date of publication of this fulltext: 13 Oct 2021 11:38

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Abstract

Background Plateletpheresis using a leukocyte reduction system (LRS) traps donor WBCs in the LRS chamber, which may lead to lymphopenia, especially in frequent plateletpheresis donors. It seems plausible that this might cause adverse effects. However, current knowledge about potential confounders and donor health impacts is incomplete. Donors and methods Recent platelet donors and donations ...