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Idiopathic pulmonary arterial hypertension phenotypes determined by cluster analysis from the COMPERA registry

Hoeper, Marius M. ; Pausch, Christine ; Grünig, Ekkehard ; Klose, Hans ; Staehler, Gerd ; Huscher, Doerte ; Pittrow, David ; Olsson, Karen M. ; Vizza, Carmine Dario ; Gall, Henning ; Benjamin, Nicola ; Distler, Oliver ; Opitz, Christian ; Gibbs, J. Simon R. ; Delcroix, Marion ; Ghofrani, H. Ardeschir ; Rosenkranz, Stephan ; Ewert, Ralf ; Kaemmerer, Harald ; Lange, Tobias J. ; Kabitz, Hans-Joachim ; Skowasch, Dirk ; Skride, Andris ; Jureviciene, Elena ; Paleviciute, Egle ; Miliauskas, Skaidrius ; Claussen, Martin ; Behr, Juergen ; Milger, Katrin ; Halank, Michael ; Wilkens, Heinrike ; Wirtz, Hubert ; Pfeuffer-Jovic, Elena ; Harbaum, Lars ; Scholtz, Werner ; Dumitrescu, Daniel ; Bruch, Leonhard ; Coghlan, Gerry ; Neurohr, Claus ; Tsangaris, Iraklis ; Gorenflo, Matthias ; Scelsi, Laura ; Vonk-Noordegraaf, Anton ; Ulrich, Silvia ; Held, Matthias



Abstract

The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients with capillary pulmonary hypertension of unknown origin. There is considerable variability in the clinical presentation of these patients. Using data from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension, we performed a cluster analysis of 841 patients with IPAH ...

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