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P. falciparum and P. vivax Orthologous Coiled-Coil Candidates for a Potential Cross-Protective Vaccine

Ayadi, Imen ; Balam, Saidou ; Audran, Régine ; Bikorimana, Jean-Pierre ; Nebie, Issa ; Diakité, Mahamadou ; Felger, Ingrid ; Tanner, Marcel ; Spertini, François ; Corradin, Giampietro ; Arevalo, Myriam ; Herrera, Socrates ; Agnolon, Valentina



Abstract

Over the last four decades, significant efforts have been invested to develop vaccines against malaria. Although most efforts are focused on the development of P. falciparum vaccines, the current availability of the parasite genomes, bioinformatics tools, and high throughput systems for both recombinant and synthetic antigen production have helped to accelerate vaccine development against the P. ...

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