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Sex steroids and autoimmune rheumatic diseases: state of the art

Cutolo, Maurizio ; Straub, Rainer H.


The effects of sex steroids (oestrogens, androgens and progesterone) on immune responses contribute to the sex bias in autoimmune rheumatic diseases in complex ways. Targeting these effects could hold potential for treating patients with autoimmune rheumatic diseases. In autoimmune rheumatic diseases, oestrogens can stimulate certain immune responses (including effects on B cells and innate ...


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