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Enhancement of Intracellular Calcium Ion Mobilization by Moderately but Not Highly Positive Material Surface Charges

Gruening, Martina ; Neuber, Sven ; Nestler, Peter ; Lehnfeld, Jutta ; Dubs, Manuela ; Fricke, Katja ; Schnabelrauch, Matthias ; Helm, Christiane A. ; Müller, Rainer ; Staehlke, Susanne ; Nebe, J. Barbara


Electrostatic forces at the cell interface affect the nature of cell adhesion and function; but there is still limited knowledge about the impact of positive or negative surface charges on cell-material interactions in regenerative medicine. Titanium surfaces with a variety of zeta potentials between -90 mV and +50 mV were generated by functionalizing them with amino polymers, extracellular ...


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